Dr. Soto and Dr. Sonnenschein discussed The Long-Term Health Threat of Endocrine Disruptors on SftPublic's Contemporary Science program in May, 2012.
The Soto Lab's focus is on the regulation of cell proliferation by sex steroids. This work is based on the premise that proliferation is the default state of all living cells. In recent work, the Soto lab identified an androgen-induced gene that mediates the state of proliferative quiescence observed in normal adult prostate epithelium.
Dr. Soto has collaborated for several decades with Professor Carlos Sonnenschein, M.D., her colleague at the Tufts University Medical School. Part of that collaboration led to the early discovery of the pernicious effect of endocrine disruptors (they coined the term), for which they (along with Dr. Patricia Hunt) received the Jacob Heskel Gabbay Award in Biotechnology and Medicine in 2012.
Dr. Soto also co-authored with Dr. Sonnenschein The Society of Cells (Bios-Springer-Verlag, 1999) in which they proposed, based on their detailed research and an exhaustive analysis of cancer research, that the so-called sporadic cancers (95 percent of all clinical cases) represent diseases specifically anchored at the tissue level of biological organization (tissue organization field theory, TOFT).
Dr. Soto's Science Watch interview about her much-cited work on endocrine disruptors